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ANGIOTENSIN CONVERTING ENZYME is blocked

Renin-Angiotensin-Aldosterone Pathway

less ANGIOTENSIN II is made

K+ not secreted from blood to urine

less K+ in urine

Adrenal cortex secretes less ALDOSTERONE

Na+/K+ ATPase not turned on

more K+ in blood

less Na+ reabsorbed from urine into blood

less water reabsorbed

blood volume not increased

blood pressure not increased

A man has taken an ACE inhibitor, which will decrease his production of angiotensin II and aldosterone. His urine potassium levels will decrease and his blood potassium levels will increase. His blood pressure will decrease.

He might develop hyperkalemia leading to cardiac arrest, and his adaptive response to the hyperkalemia could cause metabolic acidosis.

This is the end of the patho problem example. You should also be able to use this flow chart to explain the consequences of:

Renal stenosis

Hyperaldosteronism and hypoaldosteronism

renin-secreting tumors

Renin-Angiotensin-Aldosterone Pathway
less ANGIOTENSIN II is made K+ not secreted from blood to urine less K+ in urine Adrenal cortex secretes less ALDOSTERONE Na+/K+ ATPase not turned on more K+ in blood less Na+ reabsorbed from urine into blood less water reabsorbed blood volume not increased blood pressure not increased
	A man has taken an ACE inhibitor, which will decrease his production of angiotensin II and aldosterone. His urine potassium levels will decrease and his blood potassium levels will increase. His blood pressure will decrease. He might develop hyperkalemia leading to cardiac arrest, and his adaptive response to the hyperkalemia could cause metabolic acidosis. This is the end of the patho problem example. You should also be able to use this flow chart to explain the consequences of: Renal stenosis Hyperaldosteronism and hypoaldosteronism renin-secreting tumors